Bullk Product Details:
BULLK has been Re-formulated for further enhancements in:
- Rapid bulking phases
- Surges in natural strength & Mass
- Improved Libido and promotion of Alpha male mentality
- Increased Anabolism
- Improved rates of protein synthesis
At Anabolic Designs we are continually making formulas that are cutting edge and focus on quality over cost. This is why our BULLK formula has been upgraded to give consumers more value for their hard earned money without any compromise to the results our products deliver. Our products are rarely the cheapest but there's a reason we are one of the most trusted names in sports nutrition today and it's our commitment to making the best formulas, with the best ingredients, to the best science-backed research and in the best GMP registered facility in the USA.
BULLK is still powered by Bulbine Natalensis. This is still the central engine powering the BULLK matrix as this herbal dietary supplement has been shown to elicit serum testosterone increases of up to 347% over baseline and simultaneously reduce estrogen and prolactin by more than 39% - making it the absolute king of the all-natural hormone boosters.
Our new BULLK formula now has the addition of N-Methyl-D-Aspartate (NMDA) which is a known agonist for a class of glutamate receptors, the NMDA type. Synthetic NMDA elicits very strong activity for the induction of hypothalamic factors and hypophyseal hormones in mammals. Even more so, endogenous NMDA has been found to have a role in the induction of GnRH (Gonadotropin Releasing Hormone) in the hypothalamus, and of LH (Luteinizing Hormone) and GH (Growth Hormone) in the pituitary gland.
WHY USE NMDA OVER DAA?
As you are all aware DAA has been shown to be safe in dosages ranging up to 3 grams daily with no reported ill effects in humans! The testosterone increasing effect is around 42%+ and LH levels were increased by 33%+. Now 3 grams daily is a lot to fit into capsules. This is where NMDA comes into its own as it has been discovered that (100X's) lower dose of NMDA is required to elicit the same GH, Testosterone and LH release in animal models when compared to pure DAA. Both of them work, just NMDA is more potent. So this suggests it would require only 30mg of NMDA to induce the same hormone increasing effects as using 3 grams of DAA.
Occurrence of D-aspartic acid and N-methyl-D-aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth hormone release.
Using two specific and sensitive fluorometric/HPLC methods and a GC-MS method, alone and in combination with D-aspartate oxidase, we have demonstrated for the first time that N-methyl-D-aspartate (NMDA), in addition to D-aspartate (D-Asp), is endogenously present as a natural molecule in rat nervous system and endocrine glands. Both of these amino acids are mostly concentrated at nmol/g levels in the adenohypophysis, hypothalamus, brain, and testis. The adenohypophysis maximally showed the ability to accumulate D-Asp when the latter is exogenously administered. In vivo experiments, consisting of the i.p. injection of D-Asp, showed that D-Asp induced both growth hormone and luteinizing hormone (LH) release. However, in vitro experiments showed that D-Asp was able to induce LH release from adenohypophysis only when this gland was co-incubated with the hypothalamus. This is because D-Asp also induces the release of GnRH from the hypothalamus, which in turn is directly responsible for the D-Asp-induced LH secretion from the pituitary gland. Compared to D-Asp, NMDA elicits its hormone release action at concentrations approximately 100-fold lower than D-Asp. D-AP5, a specific NMDA receptor antagonist, inhibited D-Asp and NMDA hormonal activity, demonstrating that these actions are mediated by NMDA receptors.
Below is a flowchart showing the Hormone inducing pathway after ingestion of NMDA, this can be said for DAA also but as NMDA is 100X more potent this will be used for reference.
Fig - 1 is a flowchart that illustrates how NMDA acts as a hormonal activator for the Hypothalamus, Pituitary gland and the Testis. This is known as the Hypothalamic-Pituitary-Testicular axis (HPTA) and comprises three areas:
Hypothalamus: This is the master gland in the brain involved in appetite, thermoregulation and output of a vast amount of hormones. In particular it releases gonadotrophin-releasing hormone (GnHR) and growth-hormone-releasing hormone (GHRH) which controls the pituitary's release of gonadotrophins and growth hormone.
Pituitary Gland: This is workhorse of the hypothalamus. It releases the gonadotrophins, which include luteinizing hormone (LH) as well as growth hormone (GH) as well as several over hormones.
Gonads: The testes release testosterone, which as you know is one of the body's major growth hormones.
Studies have also shown that NMDA can help enhance erections so this should interest you guys out there.
The effect of 10 peptides structurally related to the growth hormone (GH) releasing peptide hexarelin, injected into the paraventricular nucleus of the hypothalamus (PVN), on penile erection was studied in male rats. Six out of the 10 peptides tested induced penile erection in a dose-dependent manner. Among them, the most potent were EP 80661, EP 60761 and EP 91072, which were active at doses of 20-200 ng. The potency of these peptides in inducing penile erection is comparable to that of apomorphine, oxytocin and N-methyl-D-aspartic acid similarly injected into the PVN. Other peptides found active were EP 50885, EP 90101 and EP 91071, which induced penile erection at doses of 200-2000 ng. In contrast, EP 51322, EP 70555, EP 51216 and EP 91073 were inactive, as were hexarelin, EP 40904 and EP 40737 in a previous study. The majority of EP peptides found active when injected into the PVN induced penile erection, although to a lesser extent, also when given systemically (endovenously). The proerectile effect of EP peptides was prevented by the oxytocin receptor antagonist [d(CH2)5 Tyr(Me)2-Orn8]-vasotocin given into the lateral ventricles but not into the PVN, by the nitric oxide (NO) synthase inhibitor N(G)-nitro-1-arginine methyl ester given either into the lateral ventricles or into the PVN, by the N-type Ca2+ channel blocker omega-conotoxin GVIA and by morphine, but not by the dopamine receptor antagonist cis-flupenthixol or by the N-methyl-D-aspartic acid receptor antagonist dizolcipine, given into the PVN. As the structure-activity relationship of EP peptides for proerectile activity is different from those of other biological actions of these compounds, ie for GH release and eating behaviour, the present results suggest that EP peptides induce penile erection by acting on specific hypothalamic receptor sites that activate paraventricular oxytocinergic neurons projecting to extrahypothalamic brain areas that mediate this sexual function by a mechanism similar to that of dopamine receptor agonists, oxytocin and N-methyl-D-aspartic acid.
The addition of NMDA will yield greater hormone increasing effects to our growing BULLK formula. As NMDA is 100x more potent than DAA then the smaller dose of NMDA can be encapsulated within our formula to further enhance results already seen from BULLK and at no extra cost.
New BULLK- Formula explained
Acetyl-Carnitine - Has the ability to cross the blood-brain barrier where it acts as a powerful antioxidant which helps prevent the brain cells deteriorate, has also been shown to improve insulin response, is a fertility booster and vital for proper energy release.
Bulbine Natalensis - The new superstar of natural anabolic hormone stimulation and central to the sheer power of the BULLK formula. It has been shown to elicit serum testosterone increases of up to 347% over baseline and simultaneously reduce estrogen and prolactin by more than 39%
Avena Sativa - A well established natural supplement extract for improving libido and testosterone output.
Resveratrol - Now known as one of the most powerful anti-oxidants involved in longevity and other health related fields, athletes have also welcomed its natural anti-estrogen control.
Beta-Ecdysterone - A naturally occurring ecosteroid, used for blood sugar control and anti-oxidant purposes also appears to have some natural anabolic activity to aid in lean muscle gains.
N-Methyl-D-Aspartate - Is an amino acid derivative and deemed 100 times more potent than D-Aspartic Acid at stimulating the NMDA receptor. NMDA can elicit extreme support for testosterone, growth hormone, IGF-1 and IGF-2.
Zinc and Vitamin D - Essential vitamin and mineral complex for regulation of proper anabolic hormone production.
For best results users of BULLK should aim to consume 1.5-2g of protein per lb of bodyweight so a 200lb male should look to ingest around 400g of protein per day. Users Under 220lbs should take 2 capsules of BULLK per day with an evening meal, users over 220lbs should take 4 capsules with an evening meal.
To ensure nutrient uptake is optimal and users have the appetite to ingest such vast amounts (2g per lb of bodyweight) of protein BULLK should be stacked with Ravenous as part of the Anabolic Designs Offseason Mass Stack.
For continual physique development cycles of the Offseason Mass stack are suggested for 8-12 weeks.
Ultimately BULLK can be stacked with Tauro-Test as part of Anabolic Designs Granite Mass Cycle for users wishing to make huge lean mass gains their goal. Increase in protein is essential to benefit from the increased protein synthesis from this stack.
Cycles of 8-12 weeks will see full benefits from the stack and ensure optimum results.
Both stacks can be followed up with 4-8 weeks of the Transform stack which incorporates Tauro-Test and ShredaBull for overall body recomposition.
These stacks are tailored to ensure maximum muscle mass, strength and performances are achieved whilst keeping healthy and looking like an elite athlete all year round!!
Bullk Supplement Facts:
Serving Size: 2 Capsules
Serving Per Container: 30
Amount Per Serving:
BullK Plex (proprietary blend) 495mg
(Acetyl-L-Carnitine, Bulbine, Avena Sativa, Resveratrol, Beta Ecdysterone, N-Methy-D-Aspartate)
Zinc 10mg 67%
Vitamin D3 1000IU 250%
Bullk Other Ingredients:
(Gelatin) Rice Flour, Magnesium Stearate, FD&C Red #40, FD&C Red #3, FD&C Blue #1.
Bullk Recommended Use:
As a dietaru supplement for best results take the following serving based on current body weight.
For users under 220 lbs body weight - take 1 serving (2 capsules) daily with an evening meal.
For users over 220 lbs body weight - take 1 1/2 to 2 servings (3-4 capsules) daily with your evening meal.
Do not exceed 4 capsules per day. Take with food and a glass of water.
Bullk Product Details: